Update: I was unfortunately not aware of Shamus Young's severe criticism of Fallout 3 available here to link in the original piece and I regret that. It dovetails rather nicely with what I've written and it's much better executed than my piece. I strongly recommend anyone...
Look out for tacks on the road, for they'll slow you down and make you crash.
Use your double-jump to get extra air over the big gaps.
Don't forget to spend your coins to upgrade your vehicle when you get the chance.