Update: I was unfortunately not aware of Shamus Young's severe criticism of Fallout 3 available here to link in the original piece and I regret that. It dovetails rather nicely with what I've written and it's much better executed than my piece. I strongly recommend anyone...
Smaller moves are more accurate than big sweeping ones, so try and stay calm.
Learn the pattern of each obstacle and you'll be ready to face whatever comes.
Give your sphere a wiggle when you start to make sure you know which way you're facing.