In all the talk of graphical downgrades no one seems much preoccupied with 'why?'. Why build something and then proceed to tear it down, piece by piece, in the hope that ever more diminished expectations about the final product won't be severe enough to...
Don't specialise. Upgrade all of your skills as you play.
Gold hangs around for a long time so don't chase it until you've cleared a screen.
Smash stuff that looks smashable, but be ready for monsters to jump out at you.