Mercenaries mode costumes
Earn an "A" rank in Mercenaries mode with the indicated character to unlock the corresponding costume.
- Pirate Leon - Earn an "A" rank as Leon.
- Puffy Jacket Jake - Earn an "A" rank as Jake.
- R.P.D. Helena - Earn an "A" rank as Helena.
- Racer Piers - Earn an "A" rank as Piers.
- Samurai Chris - Earn an "A" rank as Chris.
- School Girl Sherry - Earn an "A" rank as Sherry.
- White Dress Ada - Earn an "A" rank as Ada.
Hidden Dog Tag Title
- Curious Fun - Complete the Resident Evil 5 campaign.
Unlock Unlimited Ammo Skill
Beat all four campaigns to unlock Unlimited ammo skill for each weapon
Meet the requirement of the stage to unlock the boss.
- Gnezdo - Steel Beast - 25 Coup de grace attacks before 80 kills
- Gnezdo - High Sea Fortress - 40 melee kills before 80 kills
- Napad - Urban Chaos - 15 Counter Kills before 80 kills
- Strelat - Mining the Depths - Kill 70 enemies before 600 seconds
- Strelat - Catacombs - 20 Quick Shot Kills
- Ubistvo - Rail Yard - 25 Quick shot kills before 80 kills
Unlockable Mercenaries Characters
- Ada Wong - Complete Ada's Campaign
- Alternate Costume - With any character, receive an A ranking or higher on any level.
- BSAA Agent - Unlock every other character
- Carla Radames - Unlock every other character
- Helena Harper - Receive a B ranking or higher on Urban Chaos
- Piers Nivans - Receive a B ranking or higher on Steel Beast
- Sherry Birkin - Receive a B ranking or higher on Mining Depths
Never Run Out of Ammo with the Wing Shooter
When playing as Leon in his campaign, if you ever run out of extra ammunition, but still have a few remaining in the magazine, aim down the sights with the L trigger, then press Y to switch to Leon's duel-wielding mode. Press Y to switch back again, and you should end up with a full magazine.
Surrounded on All Sides 45 Send 2,000 enemies to your opponent's map.
Take the Stage 30 Defeat your opponent and achieve victory in 3 stages.
Killer Combo 30 Achieve a 30-combo chain.
You Are S.O.L. 10 Defeat your opponent 10 times with enemies you sent.
Kill or Be Killed 10 Win while in the dying state.
Last Man Standing--Again 45 Win five times in a row.
Take 'Em All Down 30 Defeat 100 agents.
Kung Fu Fighting 30 Survive to the end only using physical attacks.
Staying Alive 10 Return to the game as a human character.
Team Effort 10 Win without any members of your team being killed.
Not without a Fight 45 Defeat Ustanak 20 times.
Invincible 30 Defeat Ustanak without anyone on your team being captured.
Easy Pickings 30 Eliminate all players as Ustanak in less than a minute.
One Is Never Enough 10 As Ustanak, capture a total of 50 humans.
Held Captive 10 Defeat Ustanak with only one Agent remaining.
The Longest Night 10 Complete the tutorial.
Gone to Hell 15 Complete Chapter 1 in Leon's campaign.
Buried Secrets 15 Complete Chapter 2 in Leon's campaign.
Get on the Plane 15 Complete Chapter 3 in Leon's campaign.
Big Trouble in China 15 Complete Chapter 4 in Leon's campaign.
The Trouble with Women 15 Complete Chapter 5 in Leon's campaign.
Rescue the Hostages 15 Complete Chapter 1 in Chris' campaign.
Tragedy in Europe 15 Complete Chapter 2 in Chris' campaign.
After Her! 15 Complete Chapter 3 in Chris' campaign.
There's Always Hope 15 Complete Chapter 4 in Chris' campaign.
Duty Calls 15 Complete Chapter 5 in Chris' campaign.
Money Talks 15 Complete Chapter 1 in Jake's campaign.
A Revolting Development 15 Complete Chapter 2 in Jake's campaign.
Let's Blow This Joint 15 Complete Chapter 3 in Jake's campaign.
Still on the Run 15 Complete Chapter 4 in Jake's campaign.
See You Around 15 Complete Chapter 5 in Jake's campaign.
Green around the Ears 15 Complete the entire game on Amateur.
Normal Is Good 30 Complete the entire game on Normal.
Back in My Day 30 Complete the entire game on Veteran.
Leave It to the Pro 90 Complete the entire game on Professional.
Check Out My Dogs 15 Customize your dog tags.
Titular Achievement 15 Earn 10 different titles.
One Is Better Than None 15 Purchase one skill.
Mad Skillz 90 Max out all the skills that allow you to level up.
Silent Killer 15 Use a stealth attack to take down five enemies.
Finish What You Start 15 Perform a coup de grâce on ten enemies.
Bob and Weave 15 Counter an enemy's attack three times in row.
Down, Not Out 15 Defeat an enemy while dying, then recover without any help.
Lifesaver 15 Help or rescue your partner ten times.
Weapons Master 30 Use all the weapons in the game and kill ten enemies with each of them.
Give a Little Push 15 Knock ten enemies off a high place.
Rising Up 30 Earn a level-four title.
They're ACTION Figures! 15 Collect 3 figures.
Stuntman 15 Defeat 20 enemies with the Hydra using a quick shot.
Bring the Heat 15 Take down an enemy from 50 meters away with a headshot using the thermal scope.
High Voltage 15 Defeat ten enemies with a stun rod charge attack.
Zombie Massacre 15 Defeat 500 zombies.
J'avo Genocide 15 Defeat 500 J'avo.
B.O.W.s Are Ugly 30 Defeat 100 enemies that have come out of a chrysalid.
I Prefer Them Alive 15 Rescue two female survivors at the cathedral.
Flying Ace 15 Pilot the VTOL without getting a scratch on it.
Hard Choice 15 Shoot the helicopter pilot with a Magnum at point-blank range.
Covered in Brass 30 Earn 150 different medals.
Heirlooms 30 Collect all the serpent emblems.