Update: I was unfortunately not aware of Shamus Young's severe criticism of Fallout 3 available here to link in the original piece and I regret that. It dovetails rather nicely with what I've written and it's much better executed than my piece. I strongly recommend anyone...
Gameplay: Great AI, You can customize them and you have a few modes to play on as well as some cool weapons. And doing a pelvic thrust with "Fat Boy" on is hillarious.
Controls: You can make your own controls so whats the point!
Graphics/Sound: Great job, the textures and polys are done well. The splatering of a decapitated head and the blood is done well. All the weapons sound great. Music is great. But some characters look blocky.
Multiplayer: Why people bought the game, a 16 player deathmatch between pros and even a CTF match can be as exciting as the Superbowl.
Replayability: The incredible Multiplayer can keep you coming back over and over again.