The Good: Superb graphics, atmosphere, and revolutionary control setup, great use of the Wii, has all the best parts of other ports
The Bad: Graphics are starting to show age, nothing new, no downloadable content
I played RE4 to death on the PS2 and now I'm going to on the Wii. What makes the Wii version so much better is that it uses the GameCube edition's graphics, the PS2 version's extra content, plus Wii specific controls and mashes it together into on sweet combo. What's so cool about the controls is that you can now control where the gun goes via the Wii mote and you control Leon/Ashley/Ada with the C stick. This makes aiming so much easier than the gamepad. You can now use your knife with a quick swipe of the Wiimote or you can still do it the hard way.
My favorite feature is that RE4 uniquely uses the Wiimote's built in speaker. When you blow up heads, reload, shoot, jump, it all goes through the speaker and it sounds great. Capcom really put effort into this port and tried making it somewhat different. All the rest of RE4 is intact including the great story where Leon has to help rescue the President's daughter from an evil Spanish cult, the iffy voice work is still here and so is everything else. With 20 hours+ game play and the extra Ada missions you’re sure to spend loads of time with this game.