Uncharted 4: A Thief's End was revealed earlier this week during Sony's E3 press conference with a teaser trailer (see above). Aside from the fact that our treasure-hunting hero, Nathan Drake, is a bit older and has, apparently, settled down after a reckless past, we don't know much about this new PS4-exclusive adventure.
Fortunately, Naughty Dog has provided a brief overview of the narrative of A Thief's End, laying out the basic premise for what could very well be Drake's final adventure.
Several years after his last adventure, retired fortune hunter, Nathan Drake, is forced back into the world of thieves. With the stakes much more personal, Drake embarks on a globe-trotting journey in pursuit of a historical conspiracy behind a fabled pirate treasure. His greatest adventure will test his physical limits, his resolve, and ultimately what he’s willing to sacrifice to save the ones he loves.
Uncharted 4: A Thief's End is set to launch sometime next year. I'm guessing Holiday 2015.