Update: I was unfortunately not aware of Shamus Young's severe criticism of Fallout 3 available here to link in the original piece and I regret that. It dovetails rather nicely with what I've written and it's much better executed than my piece. I strongly recommend anyone...
The Prince has matured immeasurably since his courageous fight in Prince of Persia The Sands of Time. He returns here with deadlier skills, a darker heart and a craving for battle.
Our story begins a few years after the conclusion of Prince of Persia: The Sands of Time. The Prince has returned home to Babylon, to find himself hunted by a supernatural creature bent on his destruction. Forced to live a life on the run, he seeks counsel from an old mystic, who explains that his actions have spawned an immortal incarnation of Fate, known as the Dahaka. In his quest to save the Sultan's palace from destruction, the Prince created a rift in the Timeline.
Hunted by the Dahaka, the Prince embarks upon a path of both carnage and mystery to defy his preordained death. He quickly comes to realize that there's only one possible way to stay alive: journey to the birthplace of the Sands of Time, find a way to travel back into the past, and stop the Sands from being created. Without the Sands, the Prince's last adventure will not occur and the Dahaka will vanish. His journey leads him to the infernal core of a cursed island stronghold harboring mankind's greatest fears.