The following unique weapons can be purchased from vendors, obtained after completing specific quests, or looted from certain enemies.
2076 World Series Baseball Bat
Bonus: Minor chance of flying targets.
Location: Jamaica Plain City Hall reward.
Ashmaker
Bonus: Minor chance of igniting targets.
Location: Side with Fahrenheit during "The Big Dig" quest.
Automatic Laser Musket
Bonus: Automatic fire.
Location: Acquired during "The Nuclear Option" Minutemen quest.
AX90 Fury
Bonus: +50 increased damage against Super Mutants.
Location: Purchase from Teagan in the Prydwen.
Big Boy
Bonus: Fire an extra projectile.
Location: Purchase from Arturo at Diamond City.
Big Jim
Bonus: +20 chance of crippling target's legs
Location: Found inside Walden Pond.
Broadsider
Bonus: Unknown.
Location: Successfully complete the "Last Voyage Of The U.S.S. Constitution" quest.
Death From Above
Bonus: ADS with +75 increased movement speed.
Location: Reach Paladin and buy it from Proctor Teagan.
Deathclaw Gauntlet
Bonus: n/a
Location: Successfully complete the "Devil's Due" optional side-quest.
Deliverer
Bonus: n/a
Location: Successfully complete the "Tradecraft" Railroad quest.
Eddie's Peace
Bonus: Additional limb damage.
Location: Found during Detective Case Files: "Long Time Coming".
Experiment 18-A
Bonus: +25 increased rate of fire and +15 reload speed.
Location: Purchase from the Institute Requisitions in the Institute.
Final Judgment
Bonus: +25 increased rate of fire and +15 reload speed.
Location: Acquired from Elder Maxson during the "Airship Down" Institute quest or "Precipice Of War" Railroad quest.
Furious Power Fist
Bonus: Increased damage on the same target with each hit
Location: Remove the threat of Swan in Boston Common.
General Chao's Revenge
Bonus: +50 damage against robots.
Location: Purchase from Trudy in the Drumlin Diner.
Good Intentions
Bonus: Cause frenzy with critical hits.
Location: Acquired from Clint Elevated Freeway Camp.
Grognak's Axe
Bonus: Cause stagger and increased damage with bleed.
Location: Inside a display case in Hubris Comics.
HalluciGen Gas Grenade
Bonus: Cause frenzy for 60 seconds.
Location: Craft it using the material inside the basement laboratory of HalluciGen, Inc.
Homing Beacon
Bonus: Zao's sub missile strike.
Location: Successfully complete the "Here There Be Monsters" quest.
Institute Beacon
Bonus: Spawn Synths at beacon's location
Location: Successfully complete the "Airship Down" Institute quest.
Junk Jet
Bonus: Unknown.
Location: Located in the ArcJet Systems during the "Call To Arms" Brotherhood Of Steel quest.
Justice
Bonus: Cause stagger chances.
Location: Purchase from Penny in the Covenant.
Kellogg's .44 Pistol
Bonus: Fill AP with critical hits.
Location: Found during the "Reunions" main quest.
Les Fusil Teribles
Bonus: +25 limb damage with increased recoil.
Location: Found inside the Captain's cabin in Libertalia.
Lorenzo's Artifact
Bonus: Push targets away with telekinesis.
Location: Successfully complete Cabot House.
Old Faithful
Bonus: 2x damage to full-HP targets.
Location: Purchase from Arturo in Diamond City.
Partystarter
Bonus: +50 damage against human.s
Location: Purchase from KL-E-O in the Goodneighbor.
Pickman's Blade
Bonus: Increased sneak damage and bleed effects.
Location: Side with Pickman.
Prototype UP77
Bonus: Unlimited ammo.
Location: Inside a master locked safe in the University Credit Union.
Railway Rifle
Bonus: n/a
Location: Successfully complete the "Underground Undercover" Railroad quest.
Reba II
Bonus: +50 damage against Mirelurks and bugs.
Location: Help Barney during the "Barney Rook" miscellaneous quest.
Reckoning
Bonus: Take 15% decreased damage when static.
Location: Purchase from Level 4 Workshop Merchant.
Righteous Authority
Bonus: 2x damage on critical hits and refills Critical Meter 15% faster.
Location: Successfully complete the "Call To Arms" Brotherhood Of Steel quest.
Rockville Slugger
Bonus: 40% less Action Point cost.
Location: Purchase from Moe in Diamond City.
Sentinel's Plasmacaster
Bonus: 2x damage to full-HP targets.
Location: Purchase from Proctor Teagan after reaching Sentinel.
Shem Drowne's Sword
Bonus: Deal radiation damage.
Location: Found during Detective Case Files: "The Guilded Grasshopper".
Shishkebab
Bonus: Unknown.
Location: Acquired from Slag in the Blast Furnace.
Spray'n'Pray
Bonus: Bullets explode on impact dealing 15 area of effect damage.
Location: Purchase from Cricket, the caravan trader.
Survivor's Special
Bonus: Increased damage at low HP.
Location: Murder Paladin Brandis or ask him to rejoin the Brotherhood during "The Lost Patrol" Brotherhood Of Steel quest.
The Gainer
Bonus: Ignite targets for +15 area of effect damage.
Location: Successfully complete the Vitale Pumphouse number puzzle.
The Last Minute
Bonus: +50 limb damage.
Location: Purchase from Level 4 Workshop Merchant.
Tinker Tom Special
Bonus: Increased VATs accuracy while static.
Location: Purchase from Tinker Tom in the Railroad HQ.
Virgil's Rifle
Bonus: +50 against Super Mutants.
Location: Murder Virgil and loot it from him.
Wastelander's Friend
Bonus: +50 limb damage.
Location: Purchase from Deb at Bunker Hill.
Wazer Wifle
Bonus: Infinite ammo.
Location: Successfully complete Shaun's three quests.
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