Choosing the best handgun in Resident Evil 4 remake is a completely subjective process. Each of the five pistols in the base game is the best at different things. So, your choice of sidearm depends on your playstyle.
Below you’ll find the best handgun overall in Resident Evil 4 remake and what category each of the others excels in.
Resident Evil 4 remake Best Handgun Overall: Blacktail
- Power: 2.40
- Ammo Capacity: 13
- Reload Speed: 1.60
- Rate of Fire: 2.20
- Precision: 4.20
- Exclusive Upgrade: Increase power by 1.5x
When upgraded to its max, the Blacktail is the best pistol overall in Resident Evil 4. It’s nearly as powerful and precise as the Red 9 with its exclusive upgrade but has a quicker reload and rate of fire. Its biggest weakness is that it has the lowest ammo capacity, but its reload speed helps offset the fact it has three fewer rounds per magazine than the Red 9.
Most Powerful Handgun in Resident Evil 4 remake: Red 9
- Power: 2.70
- Ammo Capacity: 16
- Reload Speed: 1.25
- Rate of Fire: 1.26
- Precision: 4.80
- Exclusive Upgrade: Increase power by 1.5x
The most powerful pistol in Resident Evil 4 remake is the Red 9. The exclusive upgrade takes it from a power rating of 2.70 to 4.05, which is more powerful than any of the unupgraded rifles. On standard, it only takes 2-3 shots with the fully upgraded Red 9 to kill a standard Ganado.
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Handgun with the Highest Fire Rate in Resident Evil 4 remake: Matilda
- Power: 2.00
- Ammo Capacity: 30
- Reload Speed: 1.40
- Rate of Fire: 1.63
- Precision: 3.50
- Exclusive Upgrade: Increase ammo capacity by 2x.
Ironically, the best SMG in Resident Evil 4 remake is this pistol. When fully upgraded and equipped with its stock, the Matilda fires nearly as quickly as the TMP but is much more accurate. Its three-round bursts are excellent against Novistadors, but it’s extremely easy to waste ammo with it.
Best Handgun for Critical in Resident Evil 4 remake: SG-09 R
- Power: 2.00
- Ammo Capacity: 18
- Reload Speed: 1.40
- Rate of Fire: 1.52
- Precision: 4.00
- Exclusive Upgrade: Critical Hit Rate 5x
The SG-09 R doesn’t have the highest precision rating, but it does have an exclusive upgrade that makes it the handgun you want to use if you’re going for headshots every time. The five times critical increase means that you will be splitting heads open often, and you can equip the Laser Sight to make getting headshots a bit easier.
Best Handgun for Crowds in Resident Evil 4 remake: Punisher
- Power: 1.90
- Ammo Capacity: 24
- Reload Speed: 1.50
- Rate of Fire: 1.91
- Precision: 4.50
- Exclusive Upgrade: Penetrate through 5 targets.
The Punisher is unique among Resident Evil 4 remake’s handgun roster because it penetrates through multiple enemies. Its exclusive upgrade brings the total number of targets you can shoot through up to five at a time. This ability isn’t always the most useful, but if you’re good at luring enemies together, you can take down huge groups without using much ammo.
